INSS 2021

Heterogeneity in Obesity: Implications for Cancer and Related Obesity-Associated Outcomes

AGENDA: JUNE 21

9:00–9:10 Welcome
Elizabeth Mayer-Davis
Professor and Chair, Department of Nutrition, UNC-Chapel Hill

Session I

Obesity Heterogeneity, Metabolic Dysregulation, and the Liver:
Pathogenesis of Non-Alcoholic Fatty Liver Disease and Hepatocellular Carcinoma
Moderator: Penny Gordon-Larsen, PhD, UNC-Chapel Hill

9:10–9:40 Keynote:
Genetic Modulators of NAFLD, Alcoholic Liver Disease and Hepatocellular Carcinoma: From Discovery to Therapeutics
Yaron Rotman, MD, MsC
Clinical Investigator, National Institute of Diabetes and Digestive and Kidney Diseases

9:40–9:50 Keynote Q&A

9:50–10:05 Presentation:
Metabolic Alterations, NAFLD, and Hepatocellular Carcinoma
A. Sidney Barritt IV, MD, MSCR
Associate Professor of Medicine, Division of Gastroenterology and Hepatology, UNC-Chapel Hill

10:05–10:10 Presentation Q&A

10:10–10:25 Presentation:
Clinical Management of Obesity and Liver Disease
Kara Wegermann, MD
Trainee, Division of Gastroenterology, Duke University School of Medicine

10:25–10:30 Presentation Q&A

10:30–11:00 Panel Discussion (Discussant plus Session Speakers, with open Q&A)

Discussant:
Arion Kennedy, PhD
Assistant Professor of Molecular and Structural Biology, North Carolina State University

BREAK

11:30 - 1:00 Poster Session

SESSION II:

Inflammatory Circuits are Leads for Improving Outcomes in Obesity and Cancer
Moderator: Raz Shaikh, PhD, UNC-Chapel Hill

1:00–1:30 Keynote:
Obesity, Inflammation and Prostate Cancer Progression
John Digiovanni, PhD
Professor and Coulter R. Sublett Chair, Division of Pharmacology & Toxicology, College of Pharmacy
The University of Texas at Austin

1:30–1:40 Keynote Q&A

1:40–1:55 Presentation:
Preventing Weight Gain Alters Inflammatory Mediators in the Tumor Microenvironment
Connie J. Rogers, PhD
Associate Professor of Nutritional Sciences and Physiology, Pennsylvania State University

1:55–2:00 Presentation Q&A

2:00–2:15 Presentation:
Obesity Associated Inflammation and Postmenopausal Breast Cancer: Insights from Preclinical Models
Erin Giles, PhD
Assistant Professor of Nutrition, Texas A&M University

2:15–2:20 Presentation Q&A

2:20–2:50 Panel Discussion (Discussant plus Session Speakers, with open Q&A)

Discussant:
Erik Hanson, PhD
Assistant Professor of Exercise Physiology, UNC-Chapel Hill

SESSION III:

New Approaches for Breaking the Obesity-Cancer Link
Moderator: Stephen D. Hursting, PhD, UNC-Chapel Hill

3:00–3:30 Keynote:
Diet and Exercise Interventions for Breaking the Obesity-Breast Cancer Link
Jennifer Ligibel, MD
Associate Professor of Medicine, Harvard Medical School
Director, Leonard P. Zakim Center for Integrative Therapies and Healthy Living, Dana Farber Cancer Institute

3:30–3:40 Keynote Q&A

3:40–3:55 Presentation:
Racial Disparities in Endometrial Cancer: Intersection of Obesity and Genomics
Victoria L. Bae-Jump, MD, PhD
Professor and Fellowship Director, Gynecologic Oncology, UNC-Chapel Hill

3:55–4:00 Presentation Q&A

4:00–4:15 Presentation:
New Targets and Strategies for Breaking the Obesity-Cancer Link: Lessons from Human-Animal Co-Trials
Stephen D. Hursting, PhD
Professor, Department of Nutrition, UNC-Chapel Hill

4:15–4:20 Presentation Q&A

4:20–4:50 Panel Discussion (Discussant plus Session Speakers, with open Q&A)

Discussant:
Ximena Bustamante Marin, PhD
Assistant Professor of Nutrition, UNC-Chapel Hill

AGENDA: JUNE 22

8:30 - 9:30 INVITED ABSTRACT PRESENTATIONS
Moderator: Elizabeth Mayer-Davis
3 Abstract Presenters (To be Selected)

SESSION IV:

Drivers of Dietary Patterns and Novel Approaches to Weight Management for Cancer Prevention and Control
Moderator: Kyle Burger, PhD, Department of Nutrition, UNC-Chapel Hill

9:30–10:00 Keynote:
Neural Control of Food Intake
Hans-Rudolf Berthoud, PhD
                             George H. Bray Professor of Neurobiology and Nutrition
                              Pennington Biomedical Research Center
                               Louisiana State University

10:00–10:10 Keynote Q&A

10:10–10:25 Presentation:
Building Just-in-Time Adaptive Interventions for Weight Management
Deborah Tate, PhD
Professor, Department of Nutrition, UNC-Chapel Hill

10:25–10:30 Presentation Q&A

10:30–10:45 Presentation
Overview of eHealth/mHealth Approaches for Weight Management and Physical Activity Promotion in Cancer Survivors
Carmina Valle, PhD
Assistant Professor, Department of Nutrition, UNC-Chapel Hill

10:45–10:50 Presentation Q&A

10:50–11:20 Panel Discussion (Discussant plus Session Speakers, with open Q&A)

Discussant:
Kirsten Nyrop, PhD
Assistant Professor and Deputy Director for Research, Geriatric Oncology Program
UNC Lineberger Comprehensive Cancer Center

11:20–11:40 Presentation - Industry/Academia Partnerships
Christine May, PhD
Academic Partnership Manager
Noom, Inc.

11:40-11:50 Presentation Q&A

SESSION V: EARLY CAREER WORKSHOP

Building Interdisciplinary Research Teams
Moderators: Penny Gordon-Larsen, PhD & Raz Shaikh, PhD, Department of Nutrition, UNC-Chapel Hill

12:00–1:00 Panel Q&A and Networking